University of Miami (UM)
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Stephan Schürer, PhD is a Professor at the University of Miami (UM) Miller School of Medicine, Associate Director of Data Science at the Sylvester Comprehensive Cancer Center (SCCC), and Director of Digital Drug Discovery at the UM Institute for Data Science & Computing (IDSC). He has over 20 years of management experience in industry and academic institutions, and has served in leadership positions in several interdisciplinary geographically distributed research consortia. He has been serving as investigator in the national NIH Molecular Libraries Program (MLP) (de Souza et al. 2014; Austin et al. 2004), and as PI in the Library of Integrated Network- based Cellular Signatures (LINCS) (Evangelista et al. 2022; Pilarczyk et al. 2020; Shamsaei et al. 2020; Keenan et al. 2018), Big Data to Knowledge (BD2K) (NIH Big Data to Knowledge (BD2K) 2022; Jagodnik et al. 2017), Illuminating the Druggable Genome (IDG) (Illuminating the Druggable Genome 2022; Sheils et al. 2021; Oprea et al. 2018A,B; Cannon et al. 2017; Nguyen et al. 2017), and Rapid Acceleration of Diagnostics (RADx) (NIH Rapid Acceleration of Diagnostics (RADx) 2022; Sharkey et al. 2021). In these research consortia, he has been developing data standards (Vempati et al. 2014), ontologies such as BioAssay Ontology (BAO) (Abeyruwan et al. 2014; Visser et al. 2011) and Drug Target Ontology (DTO) (Lin et al. 2017), and informatics tools such as the LINCS Data Portal (LDP) (Koleti et al. 2018; Stathias et al. 2020) and metadata management infrastructure, tools and processes to support standardized formal descriptions, integration, and dissemination of digital resources (Stathias et al. 2018).
Recently, his group has been developing the Sylvester Data Portal (SDP) informatics platform, which is the foundation of this research infrastructure project. Schürer has worked with Dušica Vidović PhD for 15 years including in the MLP, LINCS, IDG and RADx programs. Dr. Vidović will support Schürer in managing and coordinating this project across the 6 sites. For the last 6 years, Schürer has worked with Vasileios Stathias PhD to develop the LDP, metadata management protocols, and various bioinformatics tools. Dr. Stathias is the product owner of the SDP, coordinating customer requirements, software engineering, bioinformatics processing pipelines and analysis tools, user interface design, and external data resources. In this project, Dr. Stathias will oversee the technical and scientific implementation of the PAC3R platform, working closely with Schürer. As PI of this project, Prof. Schürer will be responsible for the overall conduct, governance, and management of the project including scientific direction, technology development, ethical conduct of the project, data and software sharing, maintaining the highest standards and integrity of the performed work in the Florida CARES network, the PAC3R technology platform, presentations, progress reports, and publications. He will work closely with Dr. Kobetz, George Grills, and the other performance site PIs to advance the scientific and technology vision of the Florida CARES Network and the PAC3R technology platform.